Publication in Nature Gene Therapy
High resolution ES-DMA quantifies AAV capsid DNA content by electrical mobility to mass correlation
Highlights:
• Parallel ES-DMA and CD-MS testing demonstrates electrical mobility of aerosolized rAAVs can be directly related to particle mass.
• Electrical mobility to mass correlation enables robust identification and relative quantification of empty, full, partial, and over-filled AAV capsids by ES-DMA.
• Accessibility of sub-nanometer sizing via high resolution ES-DMA suggests utility for analytics of rAAVs and other complex biologics.
ASGCT 2026
May 2026, Boston
Luis and Preston from the NanoEngineering team present recent developments at the American Society of Gene & Cell Therapy 2026 meeting.
Download the poster here
BPS conference
Sept 2025, Boston
The Nanoengineering team presented a poster at Boston Bioprocessing Summit, here Preston Dennett and Luis Perez-Lorenzo smile with Dr. Jin Park from Ultragenyx
Download the poster here
SBIR Phase I
June 2025, NIH grant awarded
STTR Phase I
June 2025, NIH Grant awarded
Visit to Prof. Brandon Ruotolo's lab
March 2024, University of Michigan
NanoRanger temporarily installed in the laboratory of Prof. Ruotolo at University of Michigan, featuring a water CPC detector (Condensation Particle Counter) courtesy of Aerosol Dynamics and CGT collector (Condensation Growth Tube) courtesy of Aerosol devices.
Visit to Megadalton Solutions
Feb 2024, University of Indiana
NanoRanger temporarily installed on site at Megadalton Solutions.