top of page


Particle perception

We make scientific instruments that detect, quantify and characterize nano-particles in the range of 1-200 nm using the ES-DMA method.

Our systems' resolving power is superior to other ES-DMA and other methods such as IMS, DLS, and NPS.


Our systems are ideally configured for research in virology, metabolomics, bio-pharma, and environmental sciences.

Nurse Checking Girl

Our systems are primarily used for research & development in areas such as drug development, structural biology, nanoparticle manufacturing and climate research.  

To facilitate these areas of R&D, our systems are highly configurable, featuring both liquid and gas sample inputs, the most flexible electro-spray parameters of any system on the market, mutliple downstream accessories including particle counters and collectors.

Learn more about the applications for NanoEngineering's ES-DMA systems.


We are focused on advanced ES-DMA as a tool for research and the most promising way to achieve our long term mission. Electro-spray (ES) Differential Mobility Analysis (DMA) aerosolizes and ionizes a liquid sample (e.g. saliva or nasal swab), then uses the combination of an electrical field and fast flowing air to separate particles by size. 

ES-DMA focuses on particle size rather than mass or genetic composition.  The method can therefore detect and characterize known and unknown particles, including viral and LNP vectors, manufactured nanoparticles, protein complexes, and atmospheric samples.  ES-DMA also requires no reagents nor chemical reactions, promising fast results at low cost.

NanoEngineering and Yale University have recently achieved breakthrough advances in DMA resolution, enabling not only the detection but the CHARACTERIZATION of particles. NanoEngineering's contributions are focused on automation, miniaturization, and usability. 


Medical Research

Our new product, the NanoRanger system, is optimized for research  in structural virology, remnant lipoprotein particles, extracellular vesicles, and other organic metabolites in the range of 20-200 nm.

Environmental Research

Our small particle system, IonRanger, is similar to the NanoRanger except that its DMA is "tuned" for nano-particles in the 1-20nm range, including pollutants and other atmospheric particles of interest, as well as proteins and bio-markers. 

bottom of page